With 400 patients involved, it will be the largest clinical trial of manuka honey for wound care ever funded, and one of the largest leg ulcer trials in the world.
Compression bandaging is the mainstay of treatment for most leg ulcers and the trial aims to determine whether a manuka honey dressing (plus compression bandaging) is more effective at healing leg ulcers compared to usual care (plus compression bandaging) at 12 weeks.
While the use of honey for healing is not uncommon, Mr Jull says there is little solid evidence on the effect of honey on ulcer healing.
"Some research in burns does suggest that honey speeds up healing. However, the effect of honey remains unproven as a treatment for leg ulcers.
"A randomised controlled trial will provide the best evidence about whether honey aids healing," says Mr Jull.
The Clinical Trials Research Unit, in The University of Auckland's School of Population Health, is spearheading the project which includes researchers from The University of Auckland, the University of Waikato and four district health boards.
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